Program
PDF Booklet including abstracts [15Mb].
7:00 - 8:10 Breakfast and Registration
8:15 - 10:00 Morning Session 1 - Genetics Tutorial
This session will introduce concepts from human genetics, genome wide association studies, epigenomics, system genomics and beyond, and will serve as the genetic background for accepted abstracts presented in the afternoon.
- 8:15 - 8:30 Welcome Remarks
Adrian Dalca, EECS, Massachusetts Institute of Technology - 8:30 - 9:10 Progress in human genetics: GWAS and beyond
Mark Daly, Massachusetts General Hospital, Harvard Medical School
- 9:15 - 9:55 Regulatory genomics and epigenomics of complex traits and human disease
Manolis Kellis, EECS, Massachusetts Institute of Technology
10:00 - 10:30 Coffee Break
10:30 - 12:00 Morning Session 2 - Imaging Tutorial
The second morning session will begin with a clinical discussion at the intersection of imaging and genetics by Jordan Smoller. Then, Li Shen and Mert Sabuncu will then introduce concepts in imaging genetics, including computation of imaging phenotypes and current imaging genetics models and directions.
- 10:30 - 11:00 Imaging Genetics: Decoding Psychopathology
Jordan Smoller, Center for Human Genetic Research, Massachusetts General Hospital - 11:05 - 11:35 Bioinformatics Strategies for Multidimensional Brain Imaging Genetics
Li Shen, Radiology and Imaging Sciences, Indiana University School of Medicine - 11:40 - 12:00 Probing multivariate associations between structural neuroimaging phenotypes and genetic markers
Mert Sabuncu, A.A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School
12:00 - 13:00 Lunch
Please set up your posters before the end of lunch in W20-202 on boards marked with our workshop code: S-W12
13:00 - 15:00 Afternoon Session 1 - Accepted Talks and Posters - Group 1
Authors from accepted submissions will give short teaser presentations to promote their posters.
15:00 - 15:30 Coffee Break - All posters (Groups 1 and 2)
15:30 - 17:00 Afternoon Session 2 - Accepted Talks and Posters - Group 2
Authors from accepted submissions will give short teaser presentations to promote their posters.
Talks/Posters
Exact ordering of the following talks is still subject to change.
Group 1
- Correlation and integration of fMRI imaging and SNP data with sparse models
- Detection of genes associated with multiple correlated imaging phenotypes by a sparse group-ridge low-rank regression model
, Hong-Wen Deng, Vince Calhoun and Yu-Ping Wang - Probabilistic Approach to Joint Modeling of Imaging and Genetics
, Adrian Dalca, Mert Sabuncu and Polina Golland - Detecting Gene-Environment Interactions via a Kernel Machine Method
, Thomas Nichols, Debashis Ghosh, Elizabeth Mormino, Jordan Smoller and Mert Sabuncu - Fast Heritability Analysis Using Genome-Wide Data via Kernel Machines
, Thomas Nichols, Avram Holmes, Phil Lee, Joshua Roffman, Randy Buckner, Mert Sabuncu and Jordan Smoller - Longitudinal 3D MR Spectroscopic Imaging of 2-Hydroxyglutarate in patients with mutant IDH1 glioma
, Franziska Loebel, Wolfgang Bogner, Malgorzata Marjanska, Elizabeth Gerstner, Andrew Chi, Tracy Batchelor, Daniel Cahill and Bruce Rosen - Hierarchical clustering of whole genome sequence data for forecasting age of Alzheimer’s diagnosis
Rachel Yotter, Xiao Da, , Roman Filipovych and Christos Davatzikos - Genetic Determinants of Acute Cerebral Infact Volume: Results from a Preliminary Genome-Wide Associaton Study
, Kelsey Shideler, Cathy R Zhang, Adriana Perilla, Allison Kanakis, Kaitlin Fitzpatrick and Natalia S Rost - Differential Effect of 17q25 Locus on White Matter Hyperintensity Volume in Patients with Ischemic Stroke
, Lisa Cloonan, Adrian Dalca, Ramesh Sridharan, Kaitlin Fitzpatrick, Allison Kanakis, Alison M Ayres, Jonathan Rosand, Ona Wu, Polina Goland and Natalia S Rost
Group 2
- Feature Selection and Imaging-Genetics Predictions Using a Sparse, Extremely Randomized Forest Regressor
, Shantanu Sharma and Marcel Prastawa - Predictive Imaging-Genetics Models with Feature Selection and Dimension Reduction Using Sparse Partial Least Squares
Rui Li, Xiaojie Huang, Shantanu Sharma and - Investigation of biological pathways involved in brain development in preterm neonates using a multivariate phenotype and sparse regression
, James Boardman, Matt Silver, Gareth Ball, Serena Counsell, Andrew Walley, A David Edwards and Giovanni Montana - A Novel Atlas-based Approach to the Detection of Mouse Embryo Ventricular Septal Defects
, Zhongliu Xie, Asanobu Kitamoto, Masaru Tamura, Toshihiko Shiroishi and Ramamohanarao Kotagiri - Dopamine-Related Genetic Influences on Cognitive Flexibility
, Daniel Mueller, Adam Anderson and William Cunningham - Imaging Genomic Mapping of Tumor Volume MRI Phenotype in Glioblastoma and Correlation with the Survival and Treatment Response
Ginu A. Thomas, Sanjay Singh, Islam Hassan, Pascal O. Zinn and - Imaging Genomic Biomarker Signature for MGMT Promoter Methylation Identification
Ginu A. Thomas, Pascal O. Zinn and - Introduction to Imaging Genomics in Brain Tumors
, Ginu A.Thomas and Pascal O. Zinn